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Antimicrobial resistance preparedness in sub-Saharan African countries.
Antimicrobial Resistance & Infection Control ( IF 4.8 ) Pub Date : 2020-08-28 , DOI: 10.1186/s13756-020-00800-y
Linzy Elton 1 , Margaret J Thomason 1 , John Tembo 2 , Thirumalaisamy P Velavan 3, 4 , Srinivas Reddy Pallerla 3 , Liã Bárbara Arruda 1 , Francesco Vairo 5 , Chiara Montaldo 5 , Francine Ntoumi 3, 6 , Muzamil M Abdel Hamid 7 , Najmul Haider 8 , Richard Kock 8 , Giuseppe Ippolito 5 , Alimuddin Zumla 1, 9 , Timothy D McHugh 1 ,
Affiliation  

Antimicrobial resistance (AMR) is of growing concern globally and AMR status in sub-Saharan Africa (SSA) is undefined due to a lack of real-time data recording, surveillance and regulation. World Health Organization (WHO) Joint External Evaluation (JEE) reports are voluntary, collaborative processes to assess country capacities and preparedness to prevent, detect and rapidly respond to public health risks, including AMR. The data from SSA JEE reports were analysed to gain an overview of how SSA is working towards AMR preparedness and where strengths and weaknesses lie. SSA country JEE AMR preparedness scores were analysed. A cumulative mean of all the SSA country AMR preparedness scores was calculated and compared to the overall mean SSA JEE score. AMR preparedness indicators were analysed, and data were weighted by region. The mean SSA AMR preparedness score was 53% less than the overall mean SSA JEE score. East Africa had the highest percentage of countries reporting having AMR National Action Plans in place, as well as human and animal pathogen AMR surveillance programmes. Southern Africa reported the highest percentage of countries with training programmes and antimicrobial stewardship. The low mean AMR preparedness score compared to overall JEE score, along with the majority of countries lacking implemented National Action Plans, suggests that until now AMR has not been a priority for most SSA countries. By identifying regional and One Health strengths, AMR preparedness can be fortified across SSA with a multisectoral approach.

中文翻译:


撒哈拉以南非洲国家的抗菌素耐药性准备情况。



抗菌素耐药性 (AMR) 在全球范围内日益受到关注,而撒哈拉以南非洲 (SSA) 的抗菌素耐药性状况由于缺乏实时数据记录、监测和监管而未明确。世界卫生组织 (WHO) 联合外部评估 (JEE) 报告是自愿、协作的过程,旨在评估各国预防、发现和快速应对包括抗菌素耐药性在内的公共卫生风险的能力和准备情况。对 SSA JEE 报告中的数据进行了分析,以了解 SSA 如何努力做好抗微生物药物耐药性准备工作以及其优势和劣势。对 SSA 国家 JEE AMR 准备分数进行了分析。计算所有 SSA 国家 AMR 准备分数的累积平均值,并将其与 SSA JEE 总体平均分数进行比较。对抗微生物药物耐药性准备指标进行了分析,并按地区对数据进行了加权。平均 SSA AMR 准备得分比总体平均 SSA JEE 得分低 53%。东非报告已制定抗微生物药物耐药性国家行动计划以及人类和动物病原体抗微生物药物耐药性监测计划的国家比例最高。南部非洲报告说,拥有培训计划和抗菌药物管理的国家比例最高。与 JEE 总体得分相比,抗微生物药物耐药性准备情况的平均得分较低,而且大多数国家缺乏实施国家行动计划,这表明迄今为止,抗微生物药物耐药性尚未成为大多数撒哈拉以南非洲国家的优先事项。通过确定区域和 One Health 的优势,可以通过多部门方法加强整个 SSA 的抗微生物药物耐药性准备工作。
更新日期:2020-08-28
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