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Cardiovascular co-morbidity in patients with COPD in Bulgaria
Biotechnology & Biotechnological Equipment ( IF 1.5 ) Pub Date : 2020-01-01 , DOI: 10.1080/13102818.2020.1810591
Maria Dimitrova 1 , Maria Kamusheva 1 , Konstantin Tachkov 1 , Konstantin Mitov 1 , Miglena Doneva 1 , Ventsislava Pencheva 2 , Daniela Petrova 2 , Ognyan Georgiev 2 , Jordan Stoitchkov 3 , Guenka Petrova 1
Affiliation  

Abstract Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. It is also associated with significant concomitant diseases which affect the disease progression course, and contribute to the exacerbation of health status and overall mortality rate. The aim of this study was to identify the most frequent Cardio-vascular disease (CVD) comorbidities among patients with COPD in Bulgaria and their effect on the hospitalization rate, hospital stay duration and health status. A retrospective national observational study was conducted among a statistically representative cohort of 426 patients in Bulgaria. Demographic data, smoking, clinical data for COPD severity and co-morbidity were collected. Health status was assessed through the specific COPD assessment test (CAT). CVD co-morbidity was evaluated by type, considering the GOLD guidelines and number. More than 80% of the patients reported two and more CVD co-morbidities and all of them reported more than two exacerbations and more than two hospitalizations over the last year. The most frequently reported CVD co-morbidity was hypertension, which was present in 88% of the men and in 89% of the women. The data showed a positive correlation between the cardiovascular risk and the progression of the disease. Hypertension, ischemic heart disease and heart failure prevailed in the observed population. With the advancement of COPD, the number of CVDs diseases per patient and CAT score, average hospitalization rate and hospital stay increased.

中文翻译:

保加利亚 COPD 患者的心血管合并症

摘要 慢性阻塞性肺疾病 (COPD) 是全球发病率和死亡率的主要原因。它还与影响疾病进展过程的重要伴随疾病有关,并导致健康状况和总体死亡率的恶化。本研究的目的是确定保加利亚 COPD 患者中最常见的心血管疾病 (CVD) 合并症及其对住院率、住院时间和健康状况的影响。在保加利亚的 426 名具有统计代表性的队列中进行了一项回顾性全国观察性研究。收集人口统计学数据、吸烟、COPD 严重程度和合并症的临床数据。通过特定的 COPD 评估测试 (CAT) 评估健康状况。CVD 合并症按类型评估,考虑到 GOLD 指南和数量。超过 80% 的患者报告有两种或两种以上的 CVD 合并症,并且在过去一年中,所有患者都报告了两次以上的急性加重和两次以上的住院治疗。最常报告的 CVD 合并症是高血压,88% 的男性和 89% 的女性存在高血压。数据显示心血管风险与疾病进展呈正相关。高血压、缺血性心脏病和心力衰竭在观察到的人群中普遍存在。随着COPD的进展,每名患者的心血管疾病数量和CAT评分、平均住院率和住院时间均有所增加。超过 80% 的患者报告有两种或两种以上的 CVD 合并症,并且在过去一年中,所有患者都报告了两次以上的急性加重和两次以上的住院治疗。最常报告的 CVD 合并症是高血压,88% 的男性和 89% 的女性存在高血压。数据显示心血管风险与疾病进展呈正相关。高血压、缺血性心脏病和心力衰竭在观察到的人群中普遍存在。随着COPD的进展,每名患者的心血管疾病数量和CAT评分、平均住院率和住院时间均有所增加。超过 80% 的患者报告有两种或两种以上的 CVD 合并症,并且在过去一年中,所有患者都报告了两次以上的急性加重和两次以上的住院治疗。最常报告的 CVD 合并症是高血压,88% 的男性和 89% 的女性存在高血压。数据显示心血管风险与疾病进展呈正相关。高血压、缺血性心脏病和心力衰竭在观察到的人群中普遍存在。随着COPD的进展,每名患者的心血管疾病数量和CAT评分、平均住院率和住院时间均有所增加。数据显示心血管风险与疾病进展呈正相关。高血压、缺血性心脏病和心力衰竭在观察到的人群中普遍存在。随着COPD的进展,每名患者的心血管疾病数量和CAT评分、平均住院率和住院时间均有所增加。数据显示心血管风险与疾病进展呈正相关。高血压、缺血性心脏病和心力衰竭在观察到的人群中普遍存在。随着COPD的进展,每名患者的心血管疾病数量和CAT评分、平均住院率和住院时间均有所增加。
更新日期:2020-01-01
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