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Muyocopronones A and B: azaphilones from the endophytic fungus Muyocopron laterale.
Beilstein Journal of Organic Chemistry ( IF 2.7 ) Pub Date : 2020-08-28 , DOI: 10.3762/bjoc.16.177
Ken-Ichi Nakashima 1 , Junko Tomida 2 , Tomoe Tsuboi 1 , Yoshiaki Kawamura 2 , Makoto Inoue 1
Affiliation  

Two new azaphilones, namely muyocopronones A (1) and B (2), were isolated from the cultures of an endophytic fungus Muyocopron laterale ECN279. Their structures were elucidated by extensive spectroscopic analysis. Their absolute configurations were determined using the modified Mosher’s method and through comparisons of experimental and calculated electronic circular dichroism data. In addition, muyocopronone B (2) was found to exhibit a weak antibacterial activity against some Gram-positive bacteria.

中文翻译:

Muyocopronones A和B:来自内生真菌Muyocopronlaterale的氮杂苯甲酮。

从内生真菌Muyocopronlaterale ECN279的培养物中分离出两个新的氮杂苯酮,即muyocopronones A(1)和B(2)。通过广泛的光谱分析阐明了它们的结构。使用改良的Mosher方法并通过比较实验和计算出的电子圆二色性数据,确定了它们的绝对构型。此外,还发现muyocopronone B(2)对某些革兰氏阳性细菌表现出较弱的抗菌活性。
更新日期:2020-08-28
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