Exosomal miRNA‐17‐5P (Exo‐miR‐17‐5P) repressed reactive oxygen species accumulation by regulating SIRT7 in a cyclophosphamide‐induced premature ovarian insufficiency (POI) mouse model. Immunofluorescence analysis shows that expressive suppression from human umbilical cord mesenchymal stem cells in SIRT7 (red) and γH2AX (green) was weakened after Exo‐miR‐17‐5P knockdown in the POI disease. See Ding et al beginning on page 1137.

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外泌体miRNA-17-5P（Exo-miR-17-5P）通过调节环磷酰胺诱发的卵巢早衰（POI）小鼠模型中的SIRT7抑制了活性氧的积累。免疫荧光分析显示，在POI疾病中，Exo-miR-17-5P敲低后，SIRT7（红色）和γH2AX（绿色）中人脐带间充质干细胞的表达抑制作用减弱。请参阅第1137页起的Ding等人。