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Diffuse shear wave spectroscopy for soft tissue viscoelastic characterization
Ultrasonics ( IF 3.8 ) Pub Date : 2021-02-01 , DOI: 10.1016/j.ultras.2020.106239
S Beuve 1 , L Kritly 1 , S Callé 2 , J-P Remenieras 1
Affiliation  

In order to limit and slow the development of diseases, they have to be diagnosed early as possible to treat patients in a better and more rapid manner. In this paper, we focus on a noninvasive and quick method based on diffuse fields in elastography to detect diseases that affect the stiffness of organs. To validate our method, a phantom experiment numerically pre-validated is designed. It consists of seven vibrators that generate white noises in a bandwidth of [80-300] Hz and then a complex acoustic field in a phantom. Waves are tracked by a linear ultrasound probe L11-4v linked to a Verasonics Vantage System and are converted into a particle velocity 2D map as a function of time. The phase velocity of the shear waves is calculated using a temporal and 2D spatial Fourier transform and an adapted signal-processing method. Shear wave velocity dispersion measurement in the frequency bandwidth of the vibrators enables one to characterize the dynamic hardness of the material through the viscoelastic parameters μ and η in an acquisition time shorter than a second (Tacq = 300 ms). With the aim of estimating the consistency of the method, the experiment is performed N = 10 times. The measured elastic modulus and viscous parameter that quantify the dynamic properties of the medium correspond to the expected values: μ = 1.23 ± 0.05 kPa and η = 0.51 ± 0.09 Pa∙s.

中文翻译:

用于软组织粘弹性表征的漫横波谱

为了限制和减缓疾病的发展,必须尽早诊断,以便更好、更快地治疗患者。在本文中,我们专注于一种基于弹性成像中的漫射场的无创且快速的方法来检测影响器官刚度的疾病。为了验证我们的方法,设计了一个数值预验证的幻像实验。它由七个振动器组成,它们在 [80-300] Hz 的带宽内产生白噪声,然后在体模中产生复杂的声场。波由连接到 Verasonics Vantage 系统的线性超声探头 L11-4v 跟踪,并转换为作为时间函数的粒子速度二维图。剪切波的相速度是使用时间和二维空间傅立叶变换和自适应信号处理方法计算的。振动器频率带宽中的剪切波速度色散测量使人们能够在短于一秒 (Tacq = 300 ms) 的采集时间内通过粘弹性参数 μ 和 η 表征材料的动态硬度。为了估计方法的一致性,实验进行了 N = 10 次。量化介质动态特性的测量弹性模量和粘性参数对应于预期值:μ = 1.23 ± 0.05 kPa 和 η = 0.51 ± 0.09 Pa∙s。实验进行 N = 10 次。量化介质动态特性的测量弹性模量和粘性参数对应于预期值:μ = 1.23 ± 0.05 kPa 和 η = 0.51 ± 0.09 Pa∙s。实验进行 N = 10 次。量化介质动态特性的测量弹性模量和粘性参数对应于预期值:μ = 1.23 ± 0.05 kPa 和 η = 0.51 ± 0.09 Pa∙s。
更新日期:2021-02-01
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