The aim of this study was to explore hedonicity to basic tastes in patients with functional motor disorders (FMDs) that are often associated with impairment in emotional processing. We recruited 20 FMD patients and 24 healthy subjects, matched for age and sex. Subjects were asked to rate the hedonic sensation (i.e., pleasant, neutral, and unpleasant) on a − 10 to +10 scale to the four basic tastes (sweet, sour, salty, and bitter) at different concentrations, and neutral stimuli (i.e., no taste stimulation) by means of the Taste Strips Test. Anxiety, depression, and alexithymia were assessed. FMD patients rated the highest concentration of sweet taste (6.7 ± 2.6) as significantly more pleasant than controls (4.7 ± 2.5, p = 0.03), and the neutral stimuli significantly more unpleasant (patients: − 0.7 ± 0.4, controls: 0.1 ± 0.4, p = 0.013). Hedonic ratings were not correlated to anxiety, depression, or alexithymia scores. Hedonic response to taste is altered in FMD patients. This preliminary finding might result from abnormal interaction between sensory processing and emotional valence.

本研究的目的是探讨功能性运动障碍 (FMD) 患者对基本口味的享乐性，这些疾病通常与情绪处理受损有关。我们招募了 20 名 FMD 患者和 24 名健康受试者，年龄和性别相匹配。受试者被要求对不同浓度下的四种基本味道（甜味、酸味、咸味和苦味）以及中性刺激（即， ，无味觉刺激）通过味觉试纸测试。评估了焦虑、抑郁和述情障碍。FMD 患者认为最高浓度的甜味 (6.7 ± 2.6) 明显比对照者更令人愉悦 (4.7 ± 2.5, p  = 0.03)，中性刺激明显更令人不愉快 (患者：− 0.7 ± 0.4，对照者：0.1 ± 0.4 ，p  = 0.013）。享乐评级与焦虑、抑郁或述情障碍分数无关。FMD 患者对味觉的享乐反应发生了改变。这一初步发现可能是由于感觉处理和情绪效价之间的异常相互作用造成的。