Objective:

The purpose of the present study was to investigate the efficacy of combined omega-3 and Korean red ginseng supplementation on ADHD symptoms and cognitive function in children with subthreshold ADHD.

Method:

120 children from 6 to 12 years with subthreshold ADHD were enrolled in this 12-week, double-blind, randomized, placebocontrolled study. The primary outcome was measured by Attention-Deficit Hyperactivity Disorder Rating Scale (ADHD-RS). Children Behavior Check List (CBCL), and neuropsychological tests assessing attention, memory, and executive function were included as secondary primary outcome measures.

Results:

Significant effects on the scores of ADHDRS, as well as several subscales of CBCL including ADHD and attention problem subscales were revealed.

Conclusion:

The combination of omega-3 and Korean red ginseng may have beneficial effects in children with subthreshold ADHD. Increased clinical awareness of ADHD symptoms even at a subthreshold level is needed.

中文翻译：

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Omega-3 和韩国红参对亚阈下多动症儿童的疗效：一项双盲、随机、安慰剂对照试验。

客观的：

本研究的目的是调查 omega-3 和韩国红参联合补充剂对阈下 ADHD 儿童的 ADHD 症状和认知功能的疗效。

方法：

120 名 6 至 12 岁的阈下 ADHD 儿童参加了这项为期 12 周的双盲、随机、安慰剂对照研究。主要结果通过注意力缺陷多动障碍评定量表（ADHD-RS）测量。儿童行为检查表 (CBCL) 和评估注意力、记忆力和执行功能的神经心理学测试被列为次要主要结果指标。

结果：

揭示了对 ADHDRS 分数以及 CBCL 的几个分量表（包括 ADHD 和注意力问题分量表）的显着影响。

结论：

omega-3 和韩国红参的组合可能对患有阈下 ADHD 的儿童有益。即使在亚阈值水平，也需要提高对 ADHD 症状的临床认识。