Endochondral ossification is a major bone forming mechanism in vertebrates, defects in which can result in skeletal dysplasia or craniofacial anomalies in humans. The zebrafish holds great potential to advance our understanding of endochondral growth zone development and genetics, yet several important aspects of its biology remain unexplored. Here we provide a comprehensive description of endochondral growth zones in the pharyngeal skeleton, including their developmental progression, cellular activity, and adult fates.

中文翻译：

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斑马鱼咽骨骼中的软骨内生长区模式和活动。

软骨内骨化是脊椎动物的主要骨形成机制，其中的缺陷可导致人类骨骼发育不良或颅面异常。斑马鱼在促进我们对软骨内生长区发育和遗传学的理解方面具有巨大的潜力，但其生物学的几个重要方面仍有待探索。在这里，我们全面描述了咽骨骼中的软骨内生长区，包括它们的发育进程、细胞活动和成人命运。