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Inappropriate activation of invariant natural killer T cells and antigen‐presenting cells with the elevation of HMGB1 in preterm births without acute chorioamnionitis
American Journal of Reproductive Immunology ( IF 2.5 ) Pub Date : 2020-08-27 , DOI: 10.1111/aji.13330
Masahiko Kato 1, 2 , Yasuyuki Negishi 1, 3 , Yoshio Shima 4 , Yoshimitsu Kuwabara 1 , Rimpei Morita 3 , Toshiyuki Takeshita 1
Affiliation  

Acute chorioamnionitis (aCAM) associated with microbial infection is a primary cause of preterm birth (PB). However, recent studies have demonstrated that innate immunity and sterile inflammation are causes of PB in the absence of aCAM. Therefore, we analyzed immune cells in the decidua of early to moderate PB without aCAM.

中文翻译:

无急性绒毛膜羊膜炎早产中 HMGB1 升高导致不变自然杀伤 T 细胞和抗原呈递细胞的不适当激活

与微生物感染相关的急性绒毛膜羊膜炎 (aCAM) 是早产 (PB) 的主要原因。然而,最近的研究表明,在没有 aCAM 的情况下,先天免疫和无菌炎症是 PB 的原因。因此,我们在没有 aCAM 的情况下分析了早期至中度 PB 蜕膜中的免疫细胞。
更新日期:2020-08-27
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