The extracellular vesicles (EVs) research area has grown rapidly because of their pivotal roles in intercellular communications and maintaining homeostasis of individual organism. As a subtype of EVs, exosomes are made via unique biogenesis pathway and exhibit disparate functional and phenotypic characteristics. Functionally, exosomes transfer biological messages from donor cell to recipient cell, which makes exosomes as a novel therapeutic platform delivering therapeutic materials to the target tissue/cell. Currently, both academia and industry try to develop exosome platform‐based therapeutics for disease management, some of which are already in clinical trials. In this review, we will discuss focusing on therapeutic values of exosomes, recent advances in therapeutic exosome platform development, and late development of exosome therapeutics in diverse therapeutic areas.

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外泌体作为新疗法的新兴作用：生物学、技术、临床应用和未来

细胞外囊泡 (EVs) 研究领域发展迅速，因为它们在细胞间通讯和维持个体生物体内平衡方面发挥着关键作用。作为 EV 的一个亚型，外泌体是通过独特的生物发生途径并表现出不同的功能和表型特征。在功能上，外泌体将生物信息从供体细胞转移到受体细胞，这使得外泌体成为一种新型治疗平台，将治疗材料输送到靶组织/细胞。目前，学术界和工业界都在尝试开发基于外泌体平台的疾病管理疗法，其中一些已经进入临床试验。在这篇综述中，我们将重点讨论外泌体的治疗价值、治疗性外泌体平台开发的最新进展，以及外泌体疗法在不同治疗领域的后期发展。