Amino acid adducts of light fullerenes have a potential of application in a variety of fields of biomedicine, that is reactive oxygen species scavenging activity, anticancer activity, viruses and bacteria inactivation etc. In this work, the water-soluble C₆₀ fullerene derivative with l-hydroxyproline (C₆₀(C₅H₉NO₃)₂, C₆₀-Hyp) was studied. Extensive biomedical investigation of this compound, namely, antiradical activity in the reaction with stable diphenylpicrylhydrazyl radical, the binding to human serum albumin, photodynamic properties, cytotoxicity in glioblastoma A172 and lung carcinoma A549 cell lines, erythrocytes haemolysis, platelet aggregation, genotoxicity on human peripheral blood mononuclear cells was conducted. Moreover, the dynamic and structural characteristics of C₆₀-Hyp–H₂O binary system were obtained using molecular dynamic (MD) method, and size distribution along with ζ-potentials of C₆₀-Hyp associates was measured.

的光富勒烯氨基酸加合物具有应用的电势在多种生物医学领域，即活性氧自由基的活性，抗癌活性，病毒和细菌失活等。在这项工作中，水可溶性C- ₆₀与富勒烯衍生物升-羟脯氨酸（C ₆₀（C ₅ H ₉ NO ₃）₂，C ₆₀-Hyp）。该化合物的广泛生物医学研究，即与稳定的二苯基吡啶甲基肼基自由基反应的抗自由基活性，与人血清白蛋白的结合，光动力特性，胶质母细胞瘤A172和肺癌A549细胞系的细胞毒性，红细胞溶血，血小板聚集，对人外周血的基因毒性进行血液单核细胞。此外，使用分子动力学（MD）方法获得了C ₆₀ -Hyp–H ₂ O二元体系的动力学和结构特征，并测量了C ₆₀ -Hyp缔合体的尺寸分布以及ζ电位。