Three dihydrostilbene derivatives (1-3) and 5 neolignans (4-8) were isolated from the ethyl acetate-soluble fraction of Pouzolzia sanguinea. Two new compounds (1 and 4) were obtained. Their structures, as well as their absolute configuration, were elucidated by means of high-resolution electrospray ionization mass spectrometry, nuclear magnetic resonance, and circular dichroism spectral data. Compounds 1-8 inhibited NO production in lipopolysaccharide-activated BV2 cells with half-maximal inhibitory concentration (IC₅₀) values ranging from 22.7 ± 1.5 to 61.2 ± 3.1 µM. Of these, compounds 1 and 2 exhibited the most NO inhibitory activity with IC₅₀ values of 22.7 ± 1.5 and 25.1 ± 2.1 µM, respectively, in comparison with the positive control, N^G-monomethyl-L-arginine, IC₅₀ value 22.1 ± 1.2 µM.

从产于Pouzolzia sanguinea的乙酸乙酯可溶性馏分中分离出3种二氢lb衍生物（1-3）和5种新木脂素（4-8）。获得了两个新化合物（1和4）。通过高分辨率电喷雾电离质谱，核磁共振和圆二色性光谱数据阐明了它们的结构及其绝对构型。化合物1-8抑制脂多糖激活的BV2细胞中NO的产生，其最大抑制浓度（IC ₅₀）值为22.7±1.5至61.2±3.1 µM。其中，化合物1和2与IC表现出最NO抑制活性_50个22.7±1.5和25.1±2.1μM值，分别在与阳性对照相比，N ^{g ^} -单甲基-L-精氨酸，IC ₅₀值22.1±1.2μM。