ABSTRACT

Total sleep deprivation (TSD) is known to impair sustained attention. However, previously reported effects of TSD on response inhibition are mixed. We administered a “stop-signal” variation of the psychomotor vigilance test, which included 25% of trials requiring withholding of a response to assess response inhibition alongside sustained attention. Participants completed the task at baseline and after 34.5 h of wakefulness. Accuracy was not reduced during TSD. However, response times were significantly slower. A speed/accuracy trade-off allowed participants to effectively withhold responses on inhibition trials and conferred resilience of inhibitory control during TSD under conditions of relatively low time pressure.

摘要

众所周知，完全睡眠剥夺（TSD）会损害持续的注意力。但是，以前报道的TSD对反应抑制的影响是混杂的。我们进行了心理运动警惕性测试的“停止信号”变体，其中包括25％的试验需要中止反应以评估反应抑制并持续关注。参与者在基线和清醒34.5小时后完成了任务。在TSD期间，精度没有降低。但是，响应时间明显变慢。速度/精度的折衷允许参与者在相对较低的时间压力条件下有效抑制抑制试验的响应，并在TSD期间赋予抑制控制的弹性。