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The functions of kinesin and kinesin-related proteins in eukaryotes.
Cell Adhesion & Migration ( IF 3.3 ) Pub Date : 2020-08-25 , DOI: 10.1080/19336918.2020.1810939
Iftikhar Ali 1 , Wei-Cai Yang 1, 2
Affiliation  

Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work along microtubule tracks. Kinesins are found in all eukaryotic organisms and are essential to all eukaryotic cells, involved in diverse cellular functions such as microtubule dynamics and morphogenesis, chromosome segregation, spindle formation and elongation and transport of organelles. In this review, we explore recently reported functions of kinesins in eukaryotes and compare their specific cargoes in both plant and animal kingdoms to understand the possible roles of uncharacterized motors in a kingdom based on their reported functions in other kingdoms.



中文翻译:

真核生物中驱动蛋白和驱动蛋白相关蛋白的功能。

驱动蛋白构成ATP驱动的微管运动酶的超家族,其将ATP水解的化学能沿微管轨道转化为机械功。驱动蛋白存在于所有真核生物中,并且对于所有真核细胞都是必不可少的,涉及各种细胞功能,例如微管动力学和形态发生,染色体分离,纺锤体形成以及细胞器的延伸和运输。在这篇综述中,我们探索了驱动蛋白在真核生物中最近报道的功能,并比较了它们在动植物界中的特定货物,以根据其在其他王国中的报道功能了解在一个王国中未表征的马达可能发挥的作用。

更新日期:2020-08-26
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