Substance abuse affects more than one sixth of the world's population. More importantly, the nature of the abuse and the type of addictive substances available to individuals is increasing exponentially. All substances with abusive potential impact both the human immuno‐inflammatory system and oral microbial communities, and therefore play a critical role in the etiopathogenesis of periodontal diseases. Evidence strongly supports the efficacy of professionally delivered cessation counseling. Dentists, dental therapists, and hygienists are ideally placed to deliver this therapy, and to spearhead efforts to provide behavioral and pharmacologic support for cessation. The purpose of this review is to examine the biologic mechanisms underlying their role in disease causation, to understand the pharmacologic and behavioral basis for their habituation, and to investigate the efficacy of population‐based and personalized interventions in prevention of periodontal disease.

中文翻译：

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预防烟草、酒精和药物依赖者牙周病的干预措施。


药物滥用影响着世界六分之一以上的人口。更重要的是，滥用的性质和个人可获得的成瘾物质的类型正在呈指数级增长。所有具有滥用潜力的物质都会影响人类免疫炎症系统和口腔微生物群落，因此在牙周病的发病机制中发挥着关键作用。证据有力地支持了专业提供的戒烟咨询的有效性。牙医、牙科治疗师和卫生员是提供这种治疗的理想人选，并带头努力为戒烟提供行为和药物支持。本综述的目的是检查其在疾病因果关系中的生物学机制，了解其习惯的药理学和行为基础，并研究基于人群的个性化干预措施在预防牙周病方面的功效。