In neurons, teneurins and latrophilins form a juxtacrine unit that originated in the earliest metazoans. The ‘teneurin C‐terminal associated peptide’ (TCAP) regulates mitochondrial function to coordinate energy usage in surrounding cells. TCAP inhibits stress‐related actions of corticotropin‐releasing factor (CRF) in the central nervous system and may underlie the etiology of some affective disorders. More details can be found in article number 2000039 by David A. Lovejoy and David W. Hogg. Cover image by Mia Husic.

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BioEssays 9/2020

在神经元中，Teneurins和Latrophilins形成了一个最早的后生动物的并列分泌单位。“ teneurin C末端相关肽”（TCAP）调节线粒体功能以协调周围细胞的能量消耗。TCAP抑制中枢神经系统中与应激相关的促肾上腺皮质激素释放因子（CRF）的作用，并且可能是某些情感障碍的病因基础。可以在David A. Lovejoy和David W. Hogg的文章编号2000039中找到更多详细信息。封面图片由Mia Husic提供。