Bacterial elimination via the photodynamic activity of a fullerene/light-harvesting antenna molecule assembled system integrated into liposome membranes,Nanoscale Advances

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Bacterial elimination via the photodynamic activity of a fullerene/light-harvesting antenna molecule assembled system integrated into liposome membranes
Nanoscale Advances ( IF 4.6 ) Pub Date : 2020-08-25 , DOI: 10.1039/d0na00132e
Riku Kawasaki ₁ , Daiki Antoku ₁ , Reo Ohdake ₁ , Kouta Sugikawa ₁ , Atsushi Ikeda ₁

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Ease of transmission and exceptionally high mortality rates make pathogen-based infections an ongoing global threat. Herein, a facile bacterial elimination process is described which is based on the photodynamic activity of fullerenes composed of light-harvesting antenna molecules integrated into liposome membranes. This was done to expand the absorption capabilities of fullerene derivatives. Efficient energy transfer from the photoactivated antenna molecules to the fullerenes enhanced antimicrobial activity without any harmful lytic activity against red blood cells even under irradiation.

中文翻译：

通过集成到脂质体膜中的富勒烯/光捕获天线分子组装系统的光动力活性消除细菌

易于传播和极高的死亡率使基于病原体的感染成为持续的全球威胁。本文描述了一种简便的细菌消除过程，该过程基于富勒烯的光动力活性，该富勒烯由集成到脂质体膜中的光捕获天线分子组成。这样做是为了扩大富勒烯衍生物的吸收能力。从光活化天线分子到富勒烯的有效能量转移增强了抗菌活性，即使在辐照下也不会对红细胞产生任何有害的裂解活性。

更新日期：2020-10-13

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