Adaptable DNA interactions regulate surface triggered self assembly.,Nanoscale

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Adaptable DNA interactions regulate surface triggered self assembly.
Nanoscale ( IF 5.8 ) Pub Date : 2020-08-25 , DOI: 10.1039/d0nr04461j
Roberta Lanfranco ₁ , Pritam Kumar Jana , Gilles Bruylants , Pietro Cicuta , Bortolo Matteo Mognetti , Lorenzo Di Michele

Affiliation

DNA-mediated multivalent interactions between colloidal particles have been extensively applied for their ability to program bulk phase behaviour and dynamic processes. Exploiting the competition between different types of DNA–DNA bonds, here we experimentally demonstrate the selective triggering of colloidal self-assembly in the presence of a functionalised surface, which induces changes in particle–particle interactions. Besides its relevance to the manufacturing of layered materials with controlled thickness, the intrinsic signal-amplification features of the proposed interaction scheme make it valuable for biosensing applications.

中文翻译：

适应性DNA相互作用调节表面触发的自组装。

胶体粒子之间的DNA介导的多价相互作用已被广泛应用，因为它们具有编程本体相行为和动态过程的能力。利用不同类型的DNA-DNA键之间的竞争，在这里我们通过实验证明了在功能化表面的存在下胶体自组装的选择性触发，这引起了颗粒间相互作用的改变。除了与制造厚度可控的分层材料有关之外，所提出的相互作用方案的固有信号放大功能使其对于生物传感应用具有重要价值。

更新日期：2020-09-24

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