Background Few population-based studies have been conducted to determine the burden of neurological diseases in sub-Saharan Africa. A better understanding of the magnitude and impact of these disorders is pivotal to effective planning and provision of neurological services. Methods A cross-sectional survey of 2392 adults in Odeda Local Government Area, Ogun State, Southwest Nigeria was conducted between May and June 2015. Trained non-medical interviewers administered a screening instrument designed to measure the prevalence of neurological diseases and disability, while positive responders were subsequently examined by neurologists. Diagnoses were made clinically according to well-established criteria. Results The mean age of respondents was 37.2±16.1 years. A total of 842 cases of neurological diseases/disability were diagnosed in 815 individuals (26 individuals with more than one disorder). The all-cause neurological morbidity rate was 352 per 1000, while the crude prevalence rates of common neurological disorders were 304.3 per 1000 for primary headaches, 16.3 per 1000 for tropical ataxic neuropathy, 7.11 per 1000 for stroke, 5.85 per 1000 for essential tremor and 4.18 per 1000 for Parkinson’s disease. Neurological years lost due to disability was 2806.18 per 100 000. Conclusion This study provides evidence of a high neurological disease burden within the communities surveyed, which may be representative of Southwest Nigeria. In comparison with findings from previous studies within the same region, this report suggests a persistence of toxiconutritional disorders and postinfectious neurological sequelae on one hand and increased prevalence of non-communicable neurological disorders such as stroke and Parkinson’s disease.

中文翻译：

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尼日利亚西南部 Odeda 地区成人神经系统疾病负担

背景 很少有基于人群的研究来确定撒哈拉以南非洲地区神经系统疾病的负担。更好地了解这些疾病的严重程度和影响对于有效规划和提供神经系统服务至关重要。方法 2015 年 5 月至 6 月期间，对尼日利亚西南部奥贡州 Odeda 地方政府区的 2392 名成年人进行了横断面调查。经过培训的非医学访谈员使用旨在测量神经系统疾病和残疾患病率的筛查工具，而阳性随后，神经科医生对反应者进行了检查。根据公认的标准进行临床诊断。结果受访者平均年龄为37.2±16.1岁。815 人（26 人患有不止一种疾病）共诊断出 842 例神经系统疾病/残疾。全因神经系统疾病发病率为 352/1000，而常见神经系统疾病的粗发病率为：原发性头痛 304.3/1000，热带共济失调性神经病 16.3/1000，中风 7.11/1000，原发性震颤 5.85/1000，以及帕金森病每 1000 人中有 4.18 人。因残疾而损失的神经病学年数为每 100 000 人 2806.18 年。结论 本研究提供了所调查社区内神经系统疾病负担高的证据，这些社区可能代表尼日利亚西南部。与同一地区以往研究的结果相比，