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Structure of DNA polymerase ζ: capturing the getaway driver.
Nature Structural & Molecular Biology ( IF 12.5 ) Pub Date : 2020-08-25 , DOI: 10.1038/s41594-020-0502-9
M Todd Washington 1 , Melissa S Gildenberg 1
Affiliation  

During translesion synthesis, eukaryotic DNA polymerase ζ carries out extension from a wide range of DNA lesions. Elucidation of the cryo-EM structure of polymerase ζ reveals how the enzyme catalyzes DNA strand synthesis beyond the lesion.

中文翻译:


DNA聚合酶z的结构:捕获逃跑的司机。



在跨损伤合成过程中,真核 DNA 聚合酶 z 从广泛的 DNA 损伤中进行延伸。聚合酶 z 的冷冻电镜结构的阐明揭示了该酶如何催化病变之外的 DNA 链合成。
更新日期:2020-08-25
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