ABSTRACT

Night shift work suppresses excretion of melatonin, but little is known about the needed time for recovery. We aimed to compare levels of 6-sulfatoxy melatonin after three different night shift schedules, including recovery days. In a quasi-experimental, within-subject crossover study, 73 male police officers in Denmark collected morning urine after the last recovery day in three different work schedules with two, four, and seven consecutive night shifts followed by a corresponding number of days for recovery. We found no significant differences for 6‐sulphatoxymelatonin concentrations in morning urine between the three different work schedules indicating similar recovery of melatonin suppression in the studied work schedules.

摘要

夜班工作可抑制褪黑激素的排泄，但对于恢复所需的时间知之甚少。我们的目标是比较包括恢复日在内的三种不同的夜班时间表后6-巯基氧基褪黑激素的水平。在一项准实验性，跨学科交叉研究中，丹麦的73名男警务人员在最后恢复日后以三种不同的工作时间表收集了早晨的尿液，其中有两个，四个和七个连续的夜班，随后分别进行了几天的恢复。我们发现，在三个不同的工作计划之间，早晨尿液中的6-磺酰氧基褪黑激素浓度没有显着差异，这表明在研究的工作计划中褪黑激素抑制的恢复相似。