A range of preliminary designs of customised total knee implants (CTKIs) was created by resurfacing the distal femur and applying different tibial bearing surface curvatures. These were then compared with a scaled off-the-shelf symmetric total knee implant (STKI). To evaluate the biomechanical performance, a dynamic knee simulation model was created with patient-specific muscle and ankle joint loads calculated from an OpenSim musculoskeletal model. Simulation results showed the transverse curvatures of the tibial bearing surface influenced femoral mediolateral translation, while its longitudinal curvatures affected femoral adduction. Compared to the STKI, the CTKIs could restore patient knee function.

中文翻译：

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定制全膝关节植入物的胫骨轴承曲率对下蹲运动和负荷的影响

通过重修股骨远端和应用不同的胫骨支承面曲率，创建了一系列定制全膝关节植入物 (CTKI) 的初步设计。然后将这些与按比例缩放的现成对称全膝关节植入物 (STKI) 进行比较。为了评估生物力学性能，我们创建了一个动态膝关节模拟模型，其中包含从 OpenSim 肌肉骨骼模型计算出的患者特定肌肉和踝关节负荷。模拟结果显示胫骨支承面的横向曲率影响股骨内侧平移，而其纵向曲率影响股骨内收。与 STKI 相比，CTKI 可以恢复患者膝关节功能。