ABSTRACT Current theory suggests that aggressive behavior in the crayfish is largely modulated and regulated by the neurotransmitter serotonin (5-HT). To test this theory that links serotonin to aggression, we performed a series of drug treatments using various serotonin-related chemicals to measure their effects on subsequent aggressive behavior. Treatments included serotonin, the serotonin precursor tryptophan, agonists: 1-(3-chlorophenyl) piperazine (m-CPP) and 5-Carboxy, an antagonist: cinanserin, and a serotonin receptor specific neurotoxin: 5,7-dihydroxytryptamine creatinine sulfate (5,7-DHT). Significant increases in aggression of Faxonius rusticus crayfish were observed when injected with serotonin and both agonists, however no decrease in aggression occurred with the antagonist. Crayfish injected with the agonist m-CPP increased aggression but did not directly confer success in fights. Our data support the current literature that the internal aggressive state of crayfish is altered by serotonin and its agonist/antagonists, however it does not on its own improve the aggressive fighting response and/or dominance status.

中文翻译：

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与血清素相关的小龙虾攻击性改变

摘要 目前的理论表明，小龙虾的攻击行为很大程度上受神经递质血清素 (5-HT) 的调节和调节。为了验证这种将血清素与攻击性联系起来的理论，我们使用各种与血清素相关的化学物质进行了一系列药物治疗，以测量它们对随后的攻击行为的影响。治疗包括血清素、血清素前体色氨酸、激动剂：1-(3-氯苯基)哌嗪 (m-CPP) 和 5-羧基、拮抗剂：肉桂色胺和血清素受体特异性神经毒素：5,7-二羟色胺硫酸肌酐 (5 ,7-DHT）。当注射血清素和两种激动剂时，观察到 Faxonius rusticus 小龙虾的攻击性显着增加，但使用拮抗剂时攻击性没有减少。注射激动剂 m-CPP 的小龙虾增加了攻击性，但并没有直接赋予战斗成功。我们的数据支持目前的文献，即小龙虾的内部攻击状态会被 5-羟色胺及其激动剂/拮抗剂改变，但它本身并不能改善攻击性战斗反应和/或优势状态。