ABSTRACT

Several studies have provided insight into the unique intracellular localization, dynamic trafficking and diverse repertoire of binding partners of Atg9/ATG9, but structural details of the protein have remained elusive. Guardia and colleagues now report the structure of human ATG9A to a resolution of 2.9 Å, revealing, among other features, an elaborate system of tunnels permeating the ATG9A protein complex.

中文翻译：

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人类 ATG9A 的结构：你有多洞？

 抽象的

多项研究深入了解了 Atg9/ATG9 独特的细胞内定位、动态运输和不同的结合伴侣，但该蛋白质的结构细节仍然难以捉摸。 Guardia 及其同事现在以 2.9 Å 的分辨率报告了人类 ATG9A 的结构，揭示了渗透 ATG9A 蛋白质复合物的复杂隧道系统等特征。