This paper presents an inexpensive and easy‐to‐implement voltage sequencer instrument for use in microchip capillary electrophoresis (MCE) actuation. The voltage sequencer instrument takes a 0–5 V input signal from a microcontroller and produces a reciprocally proportional voltage signal with the capability to achieve the voltages required for MCE actuation. The unit developed in this work features four independent voltage channels, measures 105 × 143 × 45 mm (width × length × height), and the cost to assemble is under 60 USD. The system is controlled by a peripheral interface controller and commands are given via universal serial bus connection to a personal computer running a command line graphical user interface. The performance of the voltage sequencer is demonstrated by its integration with a fluorescence spectroscopy MCE sensor using pinched sample injection and electrophoretic separation to detect ciprofloxacin in samples of milk. This application is chosen as it is particularly important for the dairy industry, where fines and health concerns are associated with the shipping of antibiotic‐contaminated milk. The voltage sequencer instrument presented represents an effective low‐cost instrumentation method for conducting MCE, thereby making these experiments accessible and affordable for use in industries such as the dairy industry.

中文翻译：

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微芯片毛细管电泳分析的电压控制。

本文介绍了一种廉价且易于实现的电压定序器仪器，用于微芯片毛细管电泳（MCE）驱动。电压定序器仪器从微控制器获取0–5 V输入信号，并产生互成比例的电压信号，该信号能够实现MCE致动所需的电压。这项工作开发的单元具有四个独立的电压通道，尺寸为105×143×45 mm（宽×长×高），组装成本不到60美元。该系统由外围接口控制器控制，命令通过通用串行总线连接发送给运行命令行图形用户界面的个人计算机。电压定序器的性能通过与荧光光谱MCE传感器的集成来证明，该传感器使用少量样品进样和电泳分离来检测牛奶样品中的环丙沙星。选择此应用程序是因为它对乳制品行业尤为重要，因为罚款和健康问题与运输受抗生素污染的牛奶有关。提出的电压定序器仪器代表了进行MCE的一种有效的低成本仪器方法，从而使这些实验容易获得且可负担得起，可用于乳品工业等行业。罚款和健康问题与受抗生素污染的牛奶的运输有关。所介绍的电压定序器仪器代表了进行MCE的一种有效的低成本仪器方法，从而使这些实验容易获得且可负担得起，可用于乳品工业等行业。罚款和健康问题与受抗生素污染的牛奶的运输有关。提出的电压定序器仪器代表了进行MCE的一种有效的低成本仪器方法，从而使这些实验容易获得且可负担得起，可用于乳品工业等行业。