BACKGROUND Embryo Chicken Egg is a nutritional supplement used to enhance physical fitness and promote wound healing according to the traditional Chinese medicine for many years. In this study, we evaluated the effects of Embryo Chicken Egg extract (ECE) on the exercise performance and fatigue in mice and the underlying mechanisms. RESULTS The results indicated that ECE can prolong the exhaustive swimming time, decrease Lactic Acid (LA), Blood Urea Nitrogen (BUN), Creatine Kinase (CK) and Malondialdehyde (MDA) levels, and increase Superoxide Dismutase (SOD), Glutathione Peroxidase (GSH-Px) and glycogen levels. Addition, ECE can also regulate the balance of oxidative stress via AMPK/ mTOR signaling pathway. CONCLUSION Taking together, these results showed that ECE can improve exercise performance and reduce physical fatigue in mice, which indicates that ECE can be used as a potential supplement to reduce physical fatigue. This article is protected by copyright. All rights reserved.

中文翻译：

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补充胚胎鸡蛋提取物可改善小鼠的运动表现并通过 AMPK/mTOR 信号通路发挥抗疲劳作用

背景技术胚胎鸡蛋是中医多年以来用于增强体质、促进伤口愈合的营养补充剂。在这项研究中，我们评估了胚胎鸡蛋提取物 (ECE) 对小鼠运动表现和疲劳的影响及其潜在机制。结果结果表明ECE能延长力竭游泳时间，降低乳酸（LA）、血尿素氮（BUN）、肌酸激酶（CK）和丙二醛（MDA）水平，增加超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（ GSH-Px) 和糖原水平。此外，ECE还可以通过AMPK/mTOR信号通路调节氧化应激的平衡。结论 综上所述，这些结果表明 ECE 可以提高小鼠的运动表现并减少身体疲劳，这表明 ECE 可以作为减轻身体疲劳的潜在补充。本文受版权保护。版权所有。