The emerging need for accurate, efficient, inexpensive, and multiparameter monitoring of water quality has led to interest in the miniaturization of benchtop chromatography systems. This paper reports a chip-based ion chromatography (chip-IC) system in which the microvalves, sample channel, packed column, and conductivity detector are all integrated on a polymethylmethacrylate (PMMA) chip. A laser-based bonding technique was developed to guarantee simultaneous robust sealing between the homogeneous and heterogeneous interfaces. A five-electrode-based conductivity detector was presented to improve the sensitivity for nonsuppressed anion detection. Common anions (F⁻, Cl⁻, NO₃⁻, and SO₄²⁻) were separated in less than 8 min, and a detection limit (LOD) of 0.6 mg L⁻¹ was achieved for SO₄²⁻. Tap water was also analyzed using the proposed chip-IC system, and the relative deviations of the quantified concentration were less than 10% when compared with that a commercial IC system.

对水质准确、高效、廉价和多参数监测的新兴需求引起了对台式色谱系统小型化的兴趣。本文报道了一种基于芯片的离子色谱 (chip-IC) 系统，其中微型阀、样品通道、填充柱和电导检测器都集成在聚甲基丙烯酸甲酯 (PMMA) 芯片上。开发了一种基于激光的键合技术，以确保同质和异质界面之间同时进行牢固的密封。提出了一种基于五电极的电导检测器，以提高非抑制阴离子检测的灵敏度。常见阴离子（F ^-、Cl ^-、NO ₃ ^-和 SO ₄ ^2-) 的分离时间不到 8 分钟，SO ₄ ^2-的检测限 (LOD) 为 0.6 mg L ^-1。还使用建议的芯片 IC 系统分析自来水，与商业 IC 系统相比，定量浓度的相对偏差小于 10%。