Peptoids belong to a class of sequence‐controlled polymers containing N‐alkylglycine units. Ren et al. use tandem mass spectrometry to characterize the fragmentation patterns of some singly and doubly protonated peptoids with one basic residue at different positions. Upon collision‐induced dissociation, a charged peptoid dissociates into two sets of charged fragments: B‐ions, containing the N‐terminal residue (structure on the left); and Y‐ions, containing the C‐terminal residue (structure on the right). The Y‐ions are of higher abundance than the B‐ions, revealing that the C‐terminal fragments have a higher affinity toward the charge carrier, the proton. (DOI: 10.1002/bip.23358)

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类肽属于一类包含N-烷基甘氨酸单元的序列控制聚合物。任等人。使用串联质谱来表征一些在一个不同的位置带有一个碱性残基的单双质子化类肽的碎裂模式 碰撞诱导的解离后，带电的拟肽分解为两组带电的片段：B离子，包含N末端残基（左侧结构）；和Y离子，含C端残基（右侧结构）。Y离子比B离子具有更高的丰度，这表明C末端片段对电荷载体质子具有更高的亲和力。（DOI：10.1002 / bip.23358）