Isocyanates are important industrial raw materials, but they are hazardous to human health. Especially, gaseous isocyanates cause serious public health problems. Therefore, it is significant to monitor isocyanates in air. In this work, a novel ratiometric fluorescent probe based on a new fluorophore platform, which is designed by inserting a styryl π-bridge between donor and acceptor units of 1, 8-naphthalimide, was developed for quantitative detection of gaseous isocyanates. In the presence of isocyanates, fluorescence of probe solution changed from orange to yellow-green, which caused by alteration of substituent at the 4th position of styryl group resulted from reaction between isocyanates and probe, thus achieving ratiometric detection for isocyanates. And this probe exhibited a fast, sensitive and selective response towards isocyanates. Furthermore, probe solution absorption method was employed to detect quantitatively isocyanates in air. This strategy may be a powerful tool for monitoring isocyanates in air, and also provide a referable approach for detection of volatile organic compounds in air.

异氰酸酯是重要的工业原料，但它们对人体健康有害。尤其是，气态异氰酸酯会引起严重的公共卫生问题。因此，监测空气中的异氰酸酯具有重要意义。在这项工作中，开发了一种基于新型荧光团平台的新型比例荧光探针，该探针是通过在1，8-萘二甲酰亚胺的供体和受体单元之间插入苯乙烯基π桥而设计的，用于定量检测气态异氰酸酯。在异氰酸酯的存在下，探针溶液的荧光由橙色变为黄绿色，这是由于异氰酸酯与探针之间的反应导致苯乙烯基第4位取代基的改变，从而实现了异氰酸酯的比例检测。并且该探针对异氰酸酯表现出快速，灵敏和选择性的响应。此外，采用探针溶液吸收法定量检测空气中的异氰酸酯。该策略可能是监测空气中异氰酸酯的有力工具，并且还提供了检测空气中挥发性有机化合物的参考方法。