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Clinical bioinformatics for microbial genomics and metagenomics: an ESCMID Postgraduate Technical Workshop.
Microbes and Infection ( IF 2.6 ) Pub Date : 2020-08-22 , DOI: 10.1016/j.micinf.2020.07.008
Gilbert Greub 1 , Patricia M Palagi 2 , David Dylus 3 , Adrian Egli 4 , Trestan Pillonel 1 , John W A Rossen 5 , Helena M B Seth-Smith 4 , Aitana Lebrand 6 ,
Affiliation  

The European Society of Clinical Microbiology and Infectious Diseases (ESCMID) workshop on genomics and metagenomics was held in Lausanne from 9th to 12th September 2019. As many as 68 participants from 20 countries from all 5 continents participated to this postgraduate technical workshop. During 4 days, the participants shared their time between conferences on various topics related to the implementation of genomics and metagenomics in a clinical diagnostic laboratory.

These included talks from the clinics and talks from bioinformatic experts. A significant time was also dedicated to practicals covering various aspects of the data analysis of NGS sequences (quality check, annotation of virulence and antibiotic resistance genes, taxonomic assignment of amplicons, strain typing, …). This ESCMID meeting co-organized by A Lebrand and G Greub, with the help of the European Study Group for Genomics ad Molecular Diagnostics (ESGMD) provided a unique opportunity to exchange knowledge and ideas on the most recent bioinformatic approaches, as well as how to report such NGS results in diagnostic laboratories. This meeting report summarizes the key messages of this meeting.



中文翻译:

微生物基因组学和宏基因组学的临床生物信息学:ESCMID研究生技术研讨会。

2019年9月9日至12日,欧洲临床微生物学和传染病学会(基因组和宏基因组学)研讨会在洛桑举行。来自五大洲20个国家的68名参与者参加了该研究生技术研讨会。在为期4天的会议中,与会人员在两次会议之间分享了与临床诊断实验室中基因组学和宏基因组学的实施相关的各种时间。

这些包括来自诊所的演讲和来自生物信息学专家的演讲。一个重要的时间也用于实践,涉及NGS序列数据分析的各个方面(质量检查,毒力和抗生素抗性基因的注释,扩增子的分类分配,菌株分型等)。由Lebrand和G Greub共同组织的这次ESCMID会议,在欧洲基因组学和分子诊断欧洲研究小组(ESGMD)的帮助下,提供了一个难得的机会,可以就最新的生物信息学方法以及如何在诊断实验室报告此类NGS结果。该会议报告总结了该会议的主要信息。

更新日期:2020-08-22
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