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Schistosoma antigens as activators of inflammasome pathway: from an unexpected stimulus to an intriguing role.
Microbes and Infection ( IF 5.8 ) Pub Date : 2020-08-22 , DOI: 10.1016/j.micinf.2020.08.001
Rodrigo C O Sanches 1 , Cláudia Souza 1 , Sergio C Oliveira 2
Affiliation  

Parasites of the genus Schistosoma are organisms capable of living for decades within the definitive host. They interfere with the immune response by interacting with host’s receptors. In this review, we discuss from the first reports to the most recent discoveries regarding the ability of Schistosoma antigens in triggering intracellular receptors and inducing inflammasome activation.



中文翻译:

血吸虫抗原作为炎性体途径的激活剂:从意外刺激到有趣的作用。

血吸虫属的寄生虫是能够在确定宿主内生活数十年的生物。它们通过与宿主受体相互作用来干扰免疫反应。在这篇综述中,我们讨论了从第一份报告到最新发现的有关血吸虫抗原触发细胞内受体和诱导炎性体活化的能力。

更新日期:2020-08-22
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