Nutritional equivalency feeding studies with diets containing genetically modified grain continue to be required by some regulatory agencies as part of the safety assessment of new events. These studies have long been conducted using broiler chickens, as they are very sensitive to nutritional deficiencies and antinutrients in the diet owing to their very rapid growth rate. A new transgenic maize product containing event DP-2Ø2216-6 (DP202216) with enhanced grain yield potential and an herbicide-tolerance trait has been developed. The nutritional equivalency of grain produced from maize containing this event with conventional grain was evaluated in a 42-D feeding trial with male and female Ross 708 broiler chickens. Broilers consuming diets produced with grain from DP202216 maize plants performed as well and produced similar organ, carcass, and parts yields as broilers consuming diets produced with nontransgenic near-isogenic control grain. In addition, the ranges of observed performance and carcass and organ yield trait values from DP202216 and control groups were similar to the respective ranges observed for broilers fed diets containing nontransgenic commercially available maize grains. Based on these results, it is concluded that grain from DP202216 maize is nutritionally equivalent to grain from nontransgenic near-isogenic maize, consistent with previously published reports on whole-food (where the edible crop tissue is incorporated in the feed) animal feeding studies for other genetically modified events.

作为新事件安全性评估的一部分，一些管理机构仍要求使用含有转基因谷物的日粮进行营养当量喂养研究。长期以来，这些研究都是使用肉鸡进行的，因为它们的生长速度非常快，因此对饮食中的营养缺乏和抗营养成分非常敏感。包含事件DP-2Ø2216-6（DP202216的新的转基因玉米产品）具有提高的谷物单产潜力和耐除草剂性状。在雄性和雌性Ross 708肉鸡的42天饲养试验中，评估了含有这种事件的玉米所产生的谷物与常规谷物的营养等效性。食用以DP202216玉米植物的谷物生产的日粮的肉鸡也表现良好，并且产生的器官，near体和部分产量与食用非转基因近等基因对照谷物的肉鸡的日粮相似。另外，从DP202216和对照组观察到的性能，car体和器官产量性状值的范围类似于用饲喂含有非转基因市售玉米谷粒的日粮的肉鸡观察到的范围。根据这些结果，