Larix decidua is one of the fastest growing conifers and one of the most important coniferous tree species in Europe with high importance at wood-based industry; however, the bark generated from the debarking process is mainly considered as waste. This study aimed to evaluate the chemical composition and the potential of the extracts of Larix decidua bark as well as the optimization of simultaneous microwave-ultrasound assisted extraction. For this purpose, the Box-Behnken experimental design was used to evaluate the effect of extraction time, microwave power and ultrasound amplitude on the response of extraction yield. The characterization results showed high content of extractives apart from high content in phenolic compounds and high antioxidant capacity, which evidenced the potential of the raw material. Under optimal extraction conditions, 15.72 % of extraction yield was achieve. This extract was characterized by total phenolic content, total flavonoid content, antioxidant capacities (DPPH, ABTS and FRAP), high performance size exclusion chromatography and FTIR. Using simultaneous microwave-ultrasound assisted extraction increases the extraction yield to double, having also a better antioxidant capacity, and reduces the extraction time 47 times.

落叶松（落叶松）是欧洲生长最快的针叶树之一，也是最重要的针叶树种之一，在木材工业中具有很高的重要性。但是，剥皮过程中产生的树皮主要被视为废物。本研究旨在评估落叶松落叶树皮提取物的化学成分和潜力，以及同时进行微波-超声辅助提取的优化。为此，采用Box-Behnken实验设计来评估提取时间，微波功率和超声振幅对提取产率响应的影响。表征结果表明，萃取物中的酚类化合物含量高，抗氧化能力高，这证明了原料的潜力。在最佳提取条件下，15。达到72％的提取产率。该提取物的特征在于总酚含量，总黄酮含量，抗氧化能力（DPPH，ABTS和FRAP），高效尺寸排阻色谱和FTIR。同时使用微波-超声波辅助萃取可将萃取率提高一倍，同时具有更好的抗氧化能力，并将萃取时间缩短47倍。