Benchtop NMR spectrometers have become widely available over the last decade. They are now used successfully in various branches of chemistry. Their popularity continues to grow due to their low price and almost zero running costs. However, benchtop spectrometers suffer from low resolution and sensitivity compared to the high-field spectrometers used in NMR labs for several decades. In this article we present a solution for boosting the sensitivity of benchtop NMR spectrometers in a multi-scan experiment and improving their capabilities in quantitative measurement. Our solution involves the synchronized shifting of a sample to preserve its high nuclear polarization during the measurement. We performed several experiments using different samples to confirm this improved performance: an ¹H NMR experiment for 4,4-dimethoxy-2-butanone, and ¹³C NMR experiments for benzyl salicylate, the liquid pharmaceutical product Acerin (skin solution), and a mixture of m-anisaldehyde and (R)-(+)-limonene.

中文翻译：

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通过样品移动增强台式NMR光谱。

在过去的十年中，台式NMR光谱仪已经广泛使用。现在，它们已成功用于化学的各个分支。由于其低廉的价格和几乎零的运行成本，它们的受欢迎程度持续增长。但是，与NMR实验室使用了几十年的高场光谱仪相比，台式光谱仪的分辨率和灵敏度低。在本文中，我们提出了一种在多扫描实验中提高台式NMR光谱仪的灵敏度并提高其定量测量能力的解决方案。我们的解决方案涉及在测量过程中同步移动样品以保持其高核极化。我们使用不同的样本，以确认该改进的性能进行了几个实验：一个¹1 H NMR实验4,4-二甲氧基-2-丁酮，和^13个C NMR实验为水杨酸苄酯，该液体药物产品Acerin（皮肤溶液），混合物米-anisaldehyde和（- [R ）- （+） -柠檬烯。