High APOBEC1 Complementation Factor Expression Positively Modulates the Proliferation, Invasion, and Migration of Endometrial Cancer Cells Through Regulating P53/P21 Signaling Pathway,Cancer Biotherapy and Radiopharmaceuticals

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High APOBEC1 Complementation Factor Expression Positively Modulates the Proliferation, Invasion, and Migration of Endometrial Cancer Cells Through Regulating P53/P21 Signaling Pathway
Cancer Biotherapy and Radiopharmaceuticals ( IF 3.4 ) Pub Date : 2022-11-14 , DOI: 10.1089/cbr.2020.3957
Qin Liu ₁ , Chun-Yan Chen ₁ , Gui-Lin Chen ₂

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Background: APOBEC1 complementation factor (A1CF) is a component of the apolipoprotein-B messenger RNA editing complex that participates in various cellular processes and acts as an oncogene in many cancers. In this study, it was aimed to investigate the roles of A1CF and its potential mechanism in endometrial cancer (EC).

中文翻译：

APOBEC1互补因子高表达通过调控P53/P21信号通路正调控子宫内膜癌细胞的增殖、侵袭和迁移

背景： APOBEC1 互补因子 ( A1CF ) 是载脂蛋白 B 信使 RNA 编辑复合物的一个组成部分，它参与各种细胞过程并在许多癌症中充当致癌基因。本研究旨在探讨A1CF的作用及其在子宫内膜癌 (EC) 中的潜在机制。

更新日期：2022-11-15

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