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Advances in Oxosulfonylation Reaction
Advanced Synthesis & Catalysis ( IF 5.4 ) Pub Date : 2020-08-20 , DOI: 10.1002/adsc.202000647
Sumit Ghosh 1 , Sadhanendu Samanta 1 , Asim Kumar Ghosh 1 , Sukanya Neogi 1 , Alakananda Hajra 1
Affiliation  

Oxosulfonylation is a difunctionalization protocol where oxo and sulfonyl groups are introduced in one step to construct ketosulfones and N‐acylsulfonamides from simple and readily accessible reagents. The development of oxosulfonylation methods has gained significant attention due to their importance in organic and medicinal chemistry. This review article provides a brief and concise overview of the current status and latest methodologies using green oxidant and sulfonyl sources for oxosulfonylation reactions developed in the last two decades.

中文翻译:

磺酰化反应的研究进展

羰基磺酰化是一种双官能化方案,其中一步引入羰基和磺酰基,可从简单易用的试剂中构建酮砜和N-酰基磺酰胺。氧磺酰化方法的发展由于其在有机和药物化学中的重要性而受到了广泛的关注。这篇综述文章简要概述了近二十年来使用绿色氧化剂和磺酰基源进行羰基磺酰化反应的现状和最新方法。
更新日期:2020-08-20
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