The FilmArray® Pneumonia Plus (FA-PP) panel can provide rapid identifications and semiquantitative results for many pathogens. We performed a prospective single-center study in 43 critically ill patients with coronavirus disease 2019 (COVID-19) in which we performed 96 FA-PP tests and cultures of blind bronchoalveolar lavage (BBAL). FA-PP detected 1 or more pathogens in 32% (31/96 of samples), whereas culture methods detected at least 1 pathogen in 35% (34/96 of samples). The most prevalent bacteria detected were Pseudomonas aeruginosa (n = 14) and Staphylococcus aureus (n = 11) on both FA-PP and culture. The FA-PP results from BBAL in critically ill patients with COVID-19 were consistent with bacterial culture findings for bacteria present in the FA-PP panel, showing sensitivity, specificity, and positive and negative predictive value of 95%, 99%, 82%, and 100%, respectively. Median turnaround time for FA-PP was 5.5 h, which was significantly shorter than for standard culture (26 h) and antimicrobial susceptibility testing results (57 h).

FilmArray®Pneumonia Plus（FA-PP）面板可以为许多病原体提供快速鉴定和半定量结果。我们对43名2019年冠状病毒病重症患者（COVID-19）进行了一项前瞻性单中心研究，其中我们进行了96次FA-PP测试和盲支气管肺泡灌洗（BBAL）培养。FA-PP在32％（样本的31/96）中检测到1种或多种病原体，而培养方法在35％（样本的34/96）中检测到至少一种病原体。检测到的最普遍的细菌是铜绿假单胞菌（n  = 14）和金黄色葡萄球菌（n = 11）在FA-PP和文化上。BBAL的COVID-19重症患者的FA-PP结果与FA-PP面板中细菌的细菌培养结果一致，显示出敏感性，特异性以及阳性和阴性预测值分别为95％，99％，82 ％和100％。FA-PP的中位周转时间为5.5 h，明显短于标准培养（26 h）和抗菌药敏测试结果（57 h）。