A new metal-organic framework (MOF) based on Co^II ions as nodes, [Co₂(H₂O)₃(cada)](DMF)₄, which has coordinated water molecules at the occupied Co^II sites along with a suitable pore environment, was constructed by reaction of 5,5′-(9H-carbazole-2,7-diyl)diisophthalic acid (H₄cada) and Co(NO₃)₂·6H₂O in a water and DMF mixed solvent. The resulting activated MOF 1ais able to uptake considerable amounts of CO₂ at room temperature, and be further used for the efficient conversion of epoxides along with CO₂ into cyclic carbonates under mild conditions without a co-catalyst. To control intra-hospital cross-infection in the Department of Ultrasound, the anti-bacterial activity of the compound was assessed in a systemic Staphylococcus aureus infection mouse model. The survival rate of systemic Staphylococcus aureus infected mice after compound treatment was determined to evaluate protective effect of the compound in vivo. The number of colony-forming units (CFUs) in the organs of infected mice was also counted for further verification.

一种以Co ^II离子为结点的新金属有机骨架[MOF] ，[Co ₂（H ₂ O）₃（cada）]（DMF）₄，它在占据的Co ^II位点上配位了水分子，并带有合适的5,5'-（9H-咔唑-2,7-二基）二间苯二甲酸（H ₄ cada）与Co（NO ₃）₂ ·6H ₂ O在水和DMF混合溶剂中的反应可构成孔环境。所得活化的MOF 1a能够在室温下吸收大量的CO ₂，并进一步用于环氧化合物与CO ₂的有效转化在没有助催化剂的条件下在温和的条件下转化为环状碳酸酯。为了在超声科中控制医院内交叉感染，在全身性金黄色葡萄球菌感染小鼠模型中评估了该化合物的抗菌活性。测定化合物处理后全身性金黄色葡萄球菌感染的小鼠的存活率，以评估该化合物在体内的保护作用。还对感染小鼠器官中的菌落形成单位（CFU）的数量进行了计数，以进行进一步验证。