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Oropouche virus detection in saliva and urine
Memórias do Instituto Oswaldo Cruz ( IF 2.8 ) Pub Date : 2020-02-27 , DOI: 10.1590/0074-02760190338
Valdinete Alves do Nascimento 1 , João Hugo Abdalla Santos 2 , Dana Cristina da Silva Monteiro 3 , Karina Pinheiro Pessoa 1 , Antonio José Leão Cardoso 1 , Victor Costa de Souza 1 , Ligia Fernandes Abdalla 4 , Felipe Gomes Naveca 5
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Oropouche virus (OROV) is an arthropod-borne virus of the Peribunyaviridae family, transmitted to humans primarily by Culicoides paraensis. It is one of the main arboviruses infecting humans in Brazil, primarily in the Amazon Region. Here, we report the detection of OROV in the saliva and urine of a patient whose samples were collected five days after the onset of symptoms. Nucleotide sequencing and phylogenetic analysis further confirmed the results. To our knowledge, this is the first study reporting the detection of OROV in the saliva and urine of an infected patient. In addition, the results of our study expand the current knowledge pertaining to the natural history of Oropouche fever.

中文翻译:

唾液和尿液中的Oropouche病毒检测

Oropouche病毒(OROV)是Peribunyaviridae家族的一种节肢动物传播的病毒,主要通过Culicoides paraensis传播给人类。它是在巴西(主要在亚马逊地区)感染人类的​​主要虫媒病毒之一。在此,我们报告了在症状发作五天后收集样本的患者唾液和尿液中检测到OROV。核苷酸测序和系统发育分析进一步证实了结果。据我们所知,这是第一项报道检测感染患者唾液和尿液中OROV的研究。此外,我们的研究结果扩展了有关Oropouche发烧自然史的最新知识。
更新日期:2020-02-27
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