• Introduction to the Special Issue on the Belmont Report
• Franklin G. Miller and Jonathan Kimmelman

The Belmont Report, issued in 1979 by the US National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, is a landmark document providing guidance on the ethics of research involving human subjects. It is divided into three sections: (1) “Boundaries between practice and research; (2) “Basic ethical principles” (respect for persons, beneficence, and justice); and (3) “Applications of these principles with respect to informed consent, assessment of risks and benefits, and selection of subjects.”

While the Belmont Report has enduring significance, the landscape of biomedical research has changed in important ways over the past 40 years. Additionally, a large and growing body of scholarship on research ethics has been developed. This special issue of Perspectives in Biology and Medicine contains 12 essays by scholars who reflect on the ethical guidance of the Belmont Report by placing this document in historical perspective and by assessing some of its salient limitations. Individually, and collectively, these essays demonstrate that contemporary thinking about the ethics of biomedical research both builds upon the foundation laid down by the Belmont Report and necessarily moves beyond its seminal ethical guidance. [End Page 219]

• 贝尔蒙报告特刊简介
• 富兰克林 G.米勒和乔纳森 Kimmelman

Ť他贝尔蒙报告，1979年美国国家委员会生物医学和行为研究的人权保障对象发行，是一个里程碑式的文件对涉及人类受试者的研究伦理提供指导。分为三个部分：（1）“实践与研究的界限；（二）“基本伦理原则”（尊人、行善、义）；(3) “这些原则在知情同意、风险和收益评估以及受试者选择方面的应用。”

虽然贝尔蒙特报告具有持久的意义，但生物医学研究的格局在过去 40 年中发生了重大变化。此外，还开发了大量且不断增长的研究伦理学奖学金。本期《生物学与医学展望》特刊包含 12 篇学者的论文，他们通过将本文件置于历史视角并评估其一些突出局限性来反思贝尔蒙特报告的伦理指导。这些文章单独和集体地表明，当代对生物医学研究伦理的思考既建立在贝尔蒙特报告奠定的基础上，也必然超越其开创性的伦理指导。[第219页结束]