The Belmont Report has provided a useful and virtually universal framework for protecting human subjects from research abuses. However, it provides little to no guidance on the substance of human research. In an environment where major decisions concerning health-care access, funding, and regulation hinge on human research, this omission leaves downstream users of human research virtually unprotected and with few tools or frameworks to protect against a variety of practices that compromise the social value of human research. This essay advocates for the addition of a fourth principle to the Belmont three: "scientific integrity." Such a principle would seek to train human research on important social objectives while maximizing the accessibility, credibility, and generalizability of findings.

中文翻译：

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什么是人类研究？对贝尔蒙特报告遗漏科学诚信的反思

贝尔蒙特报告为保护人类受试者免受研究滥用提供了一个有用且几乎通用的框架。然而，它几乎没有提供关于人类研究实质的指导。在有关医疗保健获取、资金和监管的重大决策取决于人类研究的环境中，这种遗漏使人类研究的下游用户几乎不受保护，并且几乎没有工具或框架来防止损害社会价值的各种实践。人类研究。本文主张在贝尔蒙特三原则中增加第四项原则：“科学诚信”。这样的原则将寻求在重要的社会目标上训练人类研究，同时最大限度地提高研究结果的可及性、可信度和普遍性。