Family interventions in schizophrenia are evidence based and have been adapted to different cultural settings to improve their effectiveness and acceptability. The Arab world has a unique set of socio-cultural norms and values that cannot be ignored when developing or implementing such interventions. There is a lack of research on the feasibility of delivering family interventions for schizophrenia in the Arab region. The aim of this review is to synthesise the available evidence about culturally-adapted psychosocial family interventions in the Arab world. The review identifies the content and characteristics of these interventions, determines the strategies used to adapt them to Arab culture successfully, assesses the feasibility and acceptability of the interventions, and evaluates the effectiveness of these interventions for service users and their families. Five electronic databases were searched including MEDLINE, CINAHL, Cochrane Library, PsycINFO and EMBASE for articles written in Arabic and English from inception to August 2019. Data were extracted and synthesised narratively. Six studies were retrieved from the search: three randomised control studies, two non-randomised studies and one qualitative study. There is limited evidence about culturally-adapted family interventions in the Arab region. However, the cultural adaptation process was comprehensive, and the implementation was reported to be feasible and acceptable. The methodological quality of the included studies was generally poor, so there is a risk of underestimating the effect size of the interventions due to lack of rigour and the presence of bias. The present review provides the foundation for future work regarding family interventions in the Arab world, and confirms the feasibility of implementing such interventions with some modifications. Furthermore, the data suggests that any family-oriented intervention for schizophrenia is likely to be better than standard care in improving the outcome for patients and their families.

中文翻译：

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对阿拉伯世界精神病患者亲属的心理社会家庭干预：系统评价。

精神分裂症的家庭干预以证据为基础，并已适应不同的文化环境，以提高其有效性和可接受性。阿拉伯世界拥有一套独特的社会文化规范和价值观，在制定或实施此类干预措施时不能忽视。阿拉伯地区缺乏关于对精神分裂症进行家庭干预的可行性的研究。本次综述的目的是综合有关阿拉伯世界文化适应心理社会家庭干预措施的现有证据。审查确定了这些干预措施的内容和特点，确定了使它们成功适应阿拉伯文化的策略，评估了干预措施的可行性和可接受性，并评估了这些干预措施对服务使用者及其家庭的有效性。检索了五个电子数据库，包括 MEDLINE、CINAHL、Cochrane Library、PsycINFO 和 EMBASE，查找从成立到 2019 年 8 月用阿拉伯语和英语撰写的文章。数据以叙述方式提取和合成。从搜索中检索到六项研究：三项随机对照研究、两项非随机研究和一项定性研究。关于阿拉伯地区适应文化的家庭干预措施的证据有限。然而，文化适应过程是全面的，并且据报告实施是可行和可接受的。纳入研究的方法学质量普遍较差，因此由于缺乏严谨性和存在偏倚，存在低估干预措施效果大小的风险。本审查为阿拉伯世界家庭干预措施的未来工作奠定了基础，并确认了经过一些修改后实施此类干预措施的可行性。此外，数据表明，任何以家庭为导向的精神分裂症干预措施在改善患者及其家人的预后方面都可能比标准护理更好。