The paper of Huang et al. (Nucleic Acids Res., 2020, vol. 48, pp. 4396-4404) claims that proteins translated in different reading frames from the same mRNA can have similar functions. This conclusion is possibly incorrect due to the possibility that the wild type protein could still be expressed.

中文翻译：

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给定基因的移码蛋白不太可能保留相同的功能

Huang等人的论文。(Nucleic Acids Res., 2020, vol. 48, pp. 4396-4404) 声称从同一 mRNA 以不同阅读框架翻译的蛋白质可以具有相似的功能。由于仍有可能表达野生型蛋白质，因此该结论可能是不正确的。