Background

Clinical heterogeneity is a peculiarity of vestibular migraine, in contrast to other vestibular disorders that have a more stereotypical expression. Migraine presents a range of variability in symptoms depending on the age of the patient. Supposing that migraine headache and vestibular migraine share the same pathogenetic mechanisms, a multiparametric analysis was performed to verify the hypotheses of an age-related influence on the clinical features of vestibular migraine at the onset.

Methods

In this retrospective study, we analysed the clinical records of 72 consecutive patients affected by vestibular migraine from June 2012 to November 2018: 64 females and eight males; mean age 38.2 ± 9.6. We considered only patients that reported onset of vestibular symptoms within 12 months preceding inclusion into the study.

Results

Statistical analysis shows a significant increase in the diagnosis of probable vestibular migraine with increasing age and a decrease in vestibular migraine diagnosis (p = 0.034). The incidence of spontaneous dizziness increases with age (p = 0.012); by contrast, external spontaneous vertigo, and visually induced vertigo decrease after 40 years of age (p = 0.018), clinically characterising the onset of juvenile forms. Spontaneous vertigo, head motion-induced vertigo/dizziness, and positional vertigo did not show significant variations with age.

Conclusion

Our data show that the type of vestibular symptoms in vestibular migraine varies according to the age of onset.

中文翻译：

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前庭偏头痛发作的年龄相关特征：多参数分析。

背景

临床异质性是前庭偏头痛的一个特点，与其他具有更刻板印象的前庭疾病相反。根据患者的年龄，偏头痛表现出一系列不同的症状。假设偏头痛和前庭性偏头痛具有相同的发病机制，我们进行了多参数分析以验证年龄相关性影响前庭性偏头痛发病时的临床特征的假设。

方法

在这项回顾性研究中，我们分析了 2012 年 6 月至 2018 年 11 月连续 72 名前庭偏头痛患者的临床记录：女性 64 名，男性 8 名；平均年龄 38.2 ± 9.6。我们仅考虑了在纳入研究前 12 个月内报告出现前庭症状的患者。

结果

统计分析显示，随着年龄的增长，可能的前庭偏头痛的诊断显着增加，而前庭偏头痛的诊断显着减少（p  = 0.034）。自发性头晕的发生率随着年龄的增长而增加（p  = 0.012）；相比之下，外部自发性眩晕和视觉诱发的眩晕在 40 岁后减少 ( p  = 0.018)，临床表征为青少年型的发作。自发性眩晕、头部运动引起的眩晕/头晕和位置性眩晕没有显示出随着年龄的显着变化。

结论

我们的数据显示，前庭性偏头痛的前庭症状类型因发病年龄而异。