Background: Hematopoietic progenitor cells (HPCs) cryopreservation have applications, especially in the autologous setting, allowing therapeutic use several years after collection. Cryopreservation aims to preserve the therapeutic properties of HPCs, and successful cryopreservation depends on several factors such as preservation procedures, biopreservation media, freezing rates, and thawing procedures. In this context, the choice of the freezing bag is critical as it provides mechanical protection during the freezing process. Since Maco Biotech Freezing-ethinyl vinyl acetate (EVA) Bags^® are no longer available in our country, a comparative study was developed to verify bioequivalence with the Miltenyi CryoMACS^® freezing bag.

中文翻译：

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CryoMACS 冷冻袋与 Maco Biotech 冷冻-醋酸乙烯酯冷冻袋的比较，用于使用富含 CD34+ 的产品冷冻保存造血祖细胞。

背景：造血祖细胞 (HPC) 冷冻保存具有应用，特别是在自体环境中，允许在收集后数年用于治疗。冷冻保存旨在保留 HPC 的治疗特性，成功的冷冻保存取决于几个因素，例如保存程序、生物保存介质、冷冻速率和解冻程序。在这种情况下，冷冻袋的选择至关重要，因为它可以在冷冻过程中提供机械保护。由于 Maco Biotech 冷冻-乙炔醋酸乙烯酯 (EVA) 袋^®在我国不再可用，因此开展了一项比较研究以验证与 Miltenyi CryoMACS ^®冷冻袋的生物等效性。