Detection of re-epithelialization in wound healing is important, but challenging. Hyperspectral imaging can be used for non-destructive characterization, but efficient techniques are needed to extract and interpret the information. An inverse photon transport model suitable for characterization of re-epithelialization is validated and explored in this study. It exploits scale-invariance to enable fitting of the epidermal skin layer only. Monte Carlo simulations indicate that the fitted layer transmittance and reflectance spectra are unique, and that there exists an infinite number of coupled parameter solutions. The method is used to explain the optical behavior of and detect re-epithelialization in an in vitro wound model.

中文翻译：

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利用尺度不变性：针对伤口的高光谱图像的顶层目标逆模型

在伤口愈合中重新上皮化的检测很重要，但具有挑战性。高光谱成像可用于非破坏性表征，但是需要有效的技术来提取和解释信息。在这项研究中验证并探索了适合表征上皮细胞上皮化的逆光子传输模型。它利用尺度不变性来仅适合表皮皮肤层。蒙特卡洛模拟表明，拟合层的透射率和反射率光谱是唯一的，并且存在无限数量的耦合参数解。该方法用于解释体外伤口模型的光学行为并检测其重新上皮形成。