Advances in sequencing technologies have enabled the characterization of multiple microbial and host genomes, opening new frontiers of knowledge while kindling novel applications and research perspectives. Among these is the investigation of the viral communities residing in the human body and their impact on health and disease. To this end, the study of samples from multiple tissues is critical, yet, the complexity of such analysis calls for a dedicated pipeline. We provide an automatic and efficient pipeline for identification, assembly, and analysis of viral genomes that combines the DNA sequence data from multiple organs. TRACESPipe relies on cooperation among 3 modalities: compression-based prediction, sequence alignment, and de novo assembly. The pipeline is ultra-fast and provides, additionally, secure transmission and storage of sensitive data.

中文翻译：

---

用于多器官水平病毒基因组重建和分析的混合管道。

测序技术的进步使得多种微生物和宿主基因组的表征成为可能，开辟了新的知识领域，同时激发了新的应用和研究视角。其中包括对人体内病毒群落及其对健康和疾病的影响的调查。为此，对多个组织样本的研究至关重要，但此类分析的复杂性需要专用的流程。我们提供自动高效的流程，用于病毒基因组的识别、组装和分析，结合来自多个器官的 DNA 序列数据。TRACESPipe 依赖于 3 种模式之间的合作：基于压缩的预测、序列比对和从头组装。该管道速度超快，此外还提供敏感数据的安全传输和存储。