COVID-19 pandemic is a global calamity posing an unprecedented opportunity to study resilience. We developed a brief resilience survey probing self-reliance, emotion-regulation, interpersonal-relationship patterns and neighborhood-environment, and applied it online during the acute COVID-19 outbreak (April 6–15, 2020), on a crowdsourcing research website (www.covid19resilience.org) advertised through social media. We evaluated level of stress (worries) regarding COVID-19: (1) contracting, (2) dying from, (3) currently having, (4) family member contracting, (5) unknowingly infecting others with (6) experiencing significant financial burden following. Anxiety (GAD7) and depression (PHQ2) were measured. Totally, 3042 participants (n = 1964 females, age range 18–79, mean age = 39) completed the resilience and COVID-19-related stress survey and 1350 of them (mean age = 41, SD = 13; n = 997 females) completed GAD7 and PHQ2. Participants significantly endorsed more distress about family contracting COVID-19 (48.5%) and unknowingly infecting others (36%), than getting COVID-19 themselves (19.9%), p < 0.0005 covarying for demographics and proxy COVID-19 exposures like getting tested and knowing infected individuals. Patterns of COVID-19 related worries, rates of anxiety (GAD7 > 10, 22.2%) and depression (PHQ2 > 2, 16.1%) did not differ between healthcare providers and non-healthcare providers. Higher resilience scores were associated with lower COVID-19 related worries (main effect F_1,3054 = 134.9; p < 0.00001, covarying for confounders). Increase in 1 SD on resilience score was associated with reduced rate of anxiety (65%) and depression (69%), across healthcare and non-healthcare professionals. Findings provide empirical evidence on mental health associated with COVID-19 outbreak in a large convenience sample, setting a stage for longitudinal studies evaluating mental health trajectories following COVID-19 pandemic.

COVID-19 大流行是一场全球性灾难，为研究复原力提供了前所未有的机会。我们制定了一项简短的复原力调查，探讨自力更生、情绪调节、人际关系模式和邻里环境，并在 COVID-19 急性爆发期间（2020 年 4 月 6 日至 15 日）在众包研究网站上在线应用该调查（ www.covid19resilience.org）通过社交媒体做广告。我们评估了有关 COVID-19 的压力（担忧）水平：(1) 感染、(2) 死亡、(3) 目前感染、(4) 家庭成员感染、(5) 不知不觉地感染他人、(6) 经历重大经济损失负担如下。测量焦虑（GAD7）和抑郁（PHQ2）。总共有 3042 名参与者（ n = 1964 名女性，年龄范围 18-79，平均年龄 = 39）完成了复原力和 COVID-19 相关压力调查，其中 1350 名参与者（平均年龄 = 41，SD = 13； n = 997 名女性） ) 完成了 GAD7 和 PHQ2。参与者明显认为家庭感染 COVID-19 (48.5%) 和不知不觉地感染他人 (36%) 比自己感染 COVID-19 (19.9%) 更令人痛苦，人口统计数据和代理 COVID-19 暴露（如接受检测）的协变p < 0.0005并了解感染者。医疗保健提供者和非医疗保健提供者之间与 COVID-19 相关的担忧、焦虑（GAD7 > 10，22.2%）和抑郁（PHQ2 > 2，16.1%）的发生率没有差异。较高的复原力得分与较低的 COVID-19 相关担忧相关（主效应F _1,3054 = 134.9； p < 0.00001，混杂因素共变）。在医疗保健和非医疗保健专业人员中，复原力得分提高 1 个标准差与焦虑 (65%) 和抑郁 (69%) 发生率降低相关。 研究结果为大量方便样本中与 COVID-19 爆发相关的心理健康提供了经验证据，为评估 COVID-19 大流行后心理健康轨迹的纵向研究奠定了基础。