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Towards artificial molecular factories from framework-embedded molecular machines
Nature Reviews Chemistry ( IF 38.1 ) Pub Date : 2020-08-20 , DOI: 10.1038/s41570-020-0209-9
Simon Krause , Ben L. Feringa

Controlling cooperativity, synchronization, amplification and translation of intermolecular and intramolecular dynamics over different length scales for applications in stimuli-responsive robust solids are considered key challenges in materials sciences. In this Perspective, we discuss the possibility of embedding artificial molecular machines into heterogeneous robust frameworks with the goal of creating cooperatively working molecular factories. We describe the current progress in the design, synthesis and functioning of artificial molecular machines and outline current efforts organizing them in ordered assemblies and frameworks. On the basis of this discussion, design principles are given towards collectively working systems in which both the machine and the framework are active components. We further explore potential functionalities and applications of these systems, and discuss challenges and prospects for the future.



中文翻译:

从框架嵌入式分子机器向人工分子工厂发展

控制分子间和分子内动力学在不同长度尺度上的协同作用,同步化,扩增和翻译,以用于刺激响应性坚固的固体中,被认为是材料科学中的关键挑战。在此《观点》中,我们讨论了将人工分子机器嵌入异类健壮框架中的可能性,目的是创建可协同工作的分子工厂。我们描述了人工分子机器的设计,合成和功能方面的最新进展,并概述了目前在有序组装和框架中组织它们的工作。在此讨论的基础上,针对机器和框架都是活动组件的共同工作系统给出了设计原则。

更新日期:2020-08-20
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