Abstract Ni(Salen) complexes as an efficient, homogeneous catalysts revealed a catalytic activity toward the one-pot synthesis of tetrahydropyridine derivatives through the pseudo five-component reactions of aromatic aldehydes, aromatic amines, and β-ketoesters in ethanol at room temperature. Mild reaction conditions, good yields, high diastereoseletivity, operational simplicity, and the absence of tedious separation procedures, clean reaction profiles, high atom economy, inexpensive starting materials, and environmentally benign catalyst are the key advantages of the present MCRs protocol. Graphical Abstract

中文翻译：

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镍配合物作为四氢吡啶衍生物多组分合成的有效催化剂

摘要 Ni(Salen)配合物作为一种高效的均相催化剂，在室温下通过芳香醛、芳香胺和β-酮酯在乙醇中的假五组分反应显示出对四氢吡啶衍生物的一锅法合成的催化活性。温和的反应条件、良好的产率、高非对映选择性、操作简单、没有繁琐的分离程序、干净的反应曲线、高原子经济性、廉价的起始材料和环境友好的催化剂是本 MCRs 协议的关键优势。图形概要